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Cyclosporin D
CAS No. 63775-96-2
Cyclosporin D ( —— )
产品货号. M30364 CAS No. 63775-96-2
Cyclosporin D is a metabolite of cyclosporin A, an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
生物学信息
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产品名称Cyclosporin D
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Cyclosporin D is a metabolite of cyclosporin A, an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells.
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产品描述Cyclosporin D is a metabolite of cyclosporin A, an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells.(In Vitro):Cyclosporine D inhibits Ca2+/calmodulin dependent EF-2 phosphorylation in vitro.(In Vivo):Cyclosporine D is a potent inhibitor in vivo of phorbol ester TPA-induced biological effects in mouse skin.
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体外实验Cyclosporine D inhibits Ca2+/calmodulin dependent EF-2 phosphorylation in vitro.
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体内实验Cyclosporine D is a potent inhibitor in vivo of phorbol ester TPA-induced biological effects in mouse skin.
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同义词——
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通路Apoptosis
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靶点IL Receptor
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number63775-96-2
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分子量1216.64
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分子式C63H113N11O12
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 25 mg/mL (20.55 mM)
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SMILES——
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化学全称Sequence:cyclo ({Aaa}-Val-{Sar}-Leu-Val-Leu-Ala-Ala-Leu-Leu-{d-Val})
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
Gschwendt M, et al. The weak immunosuppressant cyclosporine D as well as the immunologically inactive cyclosporine H are potent inhibitors in vivo of phorbol ester TPA-induced biological effects in mouse skin and of Ca2+/calmodulin dependent EF-2 phosphorylation in vitro. Biochem Biophys Res Commun. 1988 Jan 29;150(2):545-51.
产品手册
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